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Series GSE173797 Query DataSets for GSE173797
Status Public on Oct 29, 2021
Title Expression (Gene) in the endothelial cells of the mouse female prefrontal cortex (PFC) following 10-day chronic social stress or 6-day subchronic variable stress exposure was compared to male [Male_SS_vs_Female_SS_or_SCVS]
Organism Mus musculus
Experiment type Expression profiling by array
Summary Cell-specific transcriptomic analysis were performed on PFC endothelial cells of stress-susceptible (SS) and resilient (RES) mice along with females subjected to 6 days of subchronic variable stress to identify novel genes and pathways involved in stress responses. These gene lists were compared to published findings obtained in the male NAc following 10 days of chronic social stress exposure (Dudek et al., 2020)
 
Overall design Animals were subject to either 10 days of chronic social defeat stress and phenotype deteremined using a social interaction test or 6 days of subchronic variable stress then the brains were collected 24h later and PFC punched for magnetic-activated cell sorting and transcriptomic analyses. Nac gene lists produced in Dudek et al. PNAS (2020)
Genome Quebec (extracted RNA, assessed quality using the bioanalyzer, performed the Clariom S mouse assay according to the manufacturer's instructions).
 
Contributor(s) Dion-Albert L, Lebel M, Menard C
Citation(s) 35013188
Submission date May 03, 2021
Last update date Jan 28, 2022
Contact name Caroline Menard
E-mail(s) Caroline.Menard@fmed.ulaval.ca
Organization name Université Laval
Department Psychiatry and Neuroscience
Lab menardneurolab.com
Street address CERVO Brain Research Center, 2601 de la Canardiere
City Quebec City
State/province QC
ZIP/Postal code G1J 2G3
Country Canada
 
Platforms (1)
GPL23038 [Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay)
Samples (29)
GSM5278676 Mouse PFC female SS 1 [CSDS_F_SS1]
GSM5278677 Mouse PFC female SS 2 [CSDS_F_SS2]
GSM5278678 Mouse PFC female SS 3 [CSDS_F_SS3]
This SubSeries is part of SuperSeries:
GSE173823 Sex-specific blood-brain barrier alterations and vascular biomarkers underlie chronic stress responses in mice and human depression.
Relations
BioProject PRJNA727161

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE173797_Female_PFC_male_NAc.xlsx 1.5 Mb (ftp)(http) XLSX
GSE173797_RAW.tar 40.2 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file
Processed data are available on Series record
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