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Series GSE176189 Query DataSets for GSE176189
Status Public on Sep 16, 2024
Title Integrative single-cell and spatial transcriptomic analyses identify a pathogenic cholangiocyte niche and TNFRSF12A as therapeutic target for biliary atresia
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Other
Summary We performed single cell 5' RNA sequencing, and B cell receptor and T cell receptor V(D)J sequencing analyses on liver biopsies of nine patients with biliary atresia and three patients with choledochal cyst at diagnosis to generate the liver cell atlas.
 
Overall design Single cell 5' RNA sequencing and V(D)J sequencing analyses of liver biopsies from nine patients with biliary atresia and three patients with choledochal cyst were collected at the time of diagnosis.
10x Genomics Chromium Next GEM Single Cell 5' RNA-seq and single cell V(D)J sequencing.

**Submitter declares that the raw data have not been provided due to patient privacy concerns**
 
Contributor(s) Luo Z
Citation(s) 39178365
Submission date Jun 04, 2021
Last update date Sep 17, 2024
Contact name Zhenhua Luo
E-mail(s) luozhh35@mail.sysu.edu.cn
Organization name The First Affiliated Hospital, Sun Yat-sen University
Street address Number 58, zhongshan er road, Yuexiu,
City Guangzhou
State/province Guangzhou
ZIP/Postal code 510080
Country China
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (36)
GSM5359592 A_CELL
GSM5359593 B_CELL
GSM5359594 C_CELL
Relations
BioProject PRJNA735239

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE176189_RAW.tar 639.3 Mb (http)(custom) TAR (of CSV, TAR)
Processed data provided as supplementary file
Raw data not provided for this record

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