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Status |
Public on Jun 15, 2021 |
Title |
Expression data of HNSCC cell lines grown without and with patient-matched CAFs in 3D |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Cancer associated fibroblasts (CAFs) are the major cellular component of the tumor microenvironment and they have been shown to stimulate tumor growth, epithelial-to-mesenchymal transition (EMT), invasion and radio-resistance. We used microarrays to investigate the influence of CAFs on the gene expression profile of HNSCC cells in 3D co-cultures
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Overall design |
HNSCC cells (LK0902, LK0917, LK1108) grown as CAF co-culture in 3D were selected for RNA extraction and hybridization on Affymetrix microarrays.
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Contributor(s) |
Wiechec E, Roberg K |
Citation(s) |
34283070 |
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Submission date |
Jun 14, 2021 |
Last update date |
Aug 11, 2021 |
Contact name |
Emilia Wiechec |
E-mail(s) |
emilia.wiechec@liu.se
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Organization name |
Linköping University
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Department |
Biomedical and Clinical Sciences
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Street address |
Sandbäcksgatan 7
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City |
Linköping |
ZIP/Postal code |
58183 |
Country |
Sweden |
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Platforms (1) |
GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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Samples (6)
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GSM5381040 |
LK0902 cell line grown without CAF in 3D |
GSM5381041 |
LK0917 cell line grown without CAF in 3D |
GSM5381042 |
LK1108 cell line grown without CAF in 3D |
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Relations |
BioProject |
PRJNA737483 |