|
| Status |
Public on May 24, 2022 |
| Title |
Chromatin Accessibility in Zebrafish Melanocytes and Melanoma Tumors [ATAC-seq] |
| Organism |
Danio rerio |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
With high genetic heterogeneity in melanoma, understanding epigenetic and transcriptional differences between melanocytes and melanoma cells will enable further understanding of the genes, pathways, and epigenetic regions influencing melanoma development. We performed RNA-seq and ATAC-seq on fluorescently-isolated melanocytes and melanoma cells from a zebrafish melanoma model.
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| |
|
| Overall design |
ATAC-seq profiles of FACS isolated mitfa:mCherry reporter positive melanocytes and crestin:GFP positive melanoma cells from adult zebrafish (D. rerio).
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| |
|
| Contributor(s) |
Kaufman CK, Kramer ET |
| Citation(s) |
34791221 |
| |
| Submission date |
Jun 24, 2021 |
| Last update date |
May 25, 2022 |
| Contact name |
Charles K Kaufman |
| E-mail(s) |
ckkaufman@wustl.edu
|
| Organization name |
Washington University in St. Louis
|
| Department |
Oncology
|
| Lab |
Kaufman
|
| Street address |
660 S Euclid Ave
|
| City |
Saint Louis |
| State/province |
MO |
| ZIP/Postal code |
63110 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18413 |
Illumina HiSeq 2500 (Danio rerio) |
|
| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE178803 |
Transcriptional Profile and Chromatin Accessibility in Zebrafish Melanocytes and Melanoma Tumors |
|
| Relations |
| BioProject |
PRJNA741110 |
| SRA |
SRP325443 |
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