Expression profiling by high throughput sequencing
Summary
The RNA-seq analysis continues our work profiling the the gastrointestinal tract of the UC Davis Type 2 Diabetes Mellitus (UCD-T2DM) Rat. Male UCD-T2DM rats (age ~170 days) were included in this study if either recently diagnosed as diabetic (n=6, RD, nonfasting glucose > 300 mg/dl) or 3-month post-onset of diabetes (n=6, D3M). A set of younger non-diabetic UCD-T2DM rats were also studied as a non-diabetic comparison (n=6, ND, age ~70 days).
Overall design
Comparison of transcriptome between UCD-T2DM rat that are non-diabetic (ND), < 1 month post-onset diabetes (RD), and 3 month post-onset diabetes (D3M)
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