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Series GSE18136 Query DataSets for GSE18136
Status Public on Oct 15, 2009
Title Punctual ablation of Foxp3+ T cells unleashes an autoimmune lesion
Organism Mus musculus
Experiment type Expression profiling by array
Summary How do Treg cells control an autoimmune lesion? We depleted Foxp3+ Treg cells in autoimmune prone TCR transgenic BDC2.5 mice on the NOD background
Kinetic of gene-expression changes in CD4 T cells isolated for pancreas and pancreas draining lymph node (PLN) of Foxp3-DTR.BDC2.5/NOD mice after Treg cell ablation

Keywords: T cell activation/ differentiation after Treg depletion timecourse
Overall design CD4 T cells were isolated from pancreas and PLN at 0, 15 and 24 hours after diphtheria toxin application into 4-6 week old female Foxp3-DTR.BDC2.5/NOD transgenic mice
Contributor(s) Feuerer M, Benoist C, Mathis D
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Submission date Sep 16, 2009
Last update date Feb 11, 2019
Contact name CBDM Lab
Phone 617-432-7747
Organization name Harvard Medical School
Department Microbiology and Immunobiology
Street address 77 Avenue Louis Pasteur
City Boston
State/province MA
ZIP/Postal code 02215
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (12)
GSM453573 P0hrno3
GSM453574 P0hrno4
GSM453575 P15hrno3
BioProject PRJNA119423

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE18136_RAW.tar 39.3 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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