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Status |
Public on Oct 15, 2004 |
Title |
Transcriptional effects of the TOR2-controlled signaling function |
Organism |
Saccharomyces cerevisiae |
Experiment type |
Expression profiling by array
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Summary |
We analysed the transcriptional effects of the TOR2-controlled signaling function using a genome-wide microarray approach in yeast. In S. cerevisiae, TOR2 has two essential signaling functions. One, shared with TOR1, is required for translation initiation, transcription, and cell growth in response to the presence of nutrients. The second is unique to TOR2, and functions in cell-cycle-dependent actin polarization and possibly in transcription. A previous genetic screen for mutants defective in the TOR-shared and the TOR2-unique functions identified several TOR2 temperature-sensitive alleles. In this study, we compared total transcription profiles for strain SH121, which is specifically defective in the TOR2-unique function, and its isogenic wild type counterpart SH100. Keywords = TOR Keywords: time-course
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Contributor(s) |
Martin DE, Demougin P, Hall MN, Bellis M |
Citation(s) |
15476558, 16959779 |
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Submission date |
Oct 01, 2004 |
Last update date |
Jul 01, 2016 |
Contact name |
Dietmar Martin |
E-mail(s) |
dietmar.martin@unibas.ch
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Phone |
0041-61-2672174
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Organization name |
Biozentrum University of Basel
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Department |
Division of Biochemistry
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Street address |
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City |
Basel |
ZIP/Postal code |
CH-4046 |
Country |
Switzerland |
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Platforms (1) |
GPL90 |
[YG_S98] Affymetrix Yeast Genome S98 Array |
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Samples (12)
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Relations |
BioProject |
PRJNA90299 |
Supplementary data files not provided |
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