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| Status |
Public on Sep 27, 2022 |
| Title |
RNA-Sequencing analysis of control and KDSR KO cancer cell lines |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The mRNA profiles of 3 cell lines (HUH7, DLD1, NCIH838) were analyzed by RNA-sequencing under control and KDSR KO conditions to identify gene expression changes induced by disruption of KDSR in cancer cells that are sensitive to its loss.
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| Overall design |
Compare the mRNA profiles of 3 cancer cell lines under CTRL (non-targeting guide) and KDSR KO mediated by CRISPR-cas9. Each condition was analyzed in biological triplicate for a total of 18 samples.
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| |
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| Contributor(s) |
Spears ME, Kim D, Li R, Zhu LJ, Torres EM |
| Citation(s) |
36170811 |
| |
| Submission date |
Aug 16, 2021 |
| Last update date |
Oct 28, 2022 |
| Contact name |
Meghan E Spears |
| E-mail(s) |
meghan.spears@umassmed.edu
|
| Organization name |
University of Massachusetts Medical School
|
| Department |
Molecular, Cell and Cancer Biology
|
| Lab |
Dohoon Kim
|
| Street address |
364 Plantation St, LRB
|
| City |
Worcester |
| State/province |
MA |
| ZIP/Postal code |
01605 |
| Country |
USA |
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| Platforms (1) |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA755272 |
| SRA |
SRP332698 |
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