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Series GSE182520 Query DataSets for GSE182520
Status Public on Aug 27, 2021
Title Human retinal organoids release extracellular vesicles that regulate gene expression in target human retinal progenitors
Organisms Homo sapiens; blank sample
Experiment type Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
Summary Developing human retinal organoids and their EVs contain unique populations of small noncoding RNAs, including miRNA, piRNA and tRNA. The EV genetic cargo has functions correlated to retinal differentiation and development. Retinal organoid EVs educate multipotent retinal progenitor cell differentiation toward photoreceptor and ganglion cell fates.
Overall design Human retinal organoid EV miRNA cargo and their effect on target human retinal progenitor cells mRNA expression characterized.
Contributor(s) Canto-Soler MV, Redenti S
Citation(s) 34702879
Submission date Aug 20, 2021
Last update date Nov 03, 2021
Contact name Stephen Redenti
Phone 6468725363
Organization name Lehman College, CUNY
Lab Science Hall 3402
Street address Biology Dept. , 250 Bedford Park Blvd.
City Bronx
State/province NY
ZIP/Postal code 10468
Country USA
Platforms (3)
GPL15520 Illumina MiSeq (Homo sapiens)
GPL17303 Ion Torrent Proton (Homo sapiens)
GPL27039 Illumina MiSeq (blank sample)
Samples (21)
GSM5530736 Control Media - D42A
GSM5530737 Experimental Media - D90A
GSM5530738 Experimental Media - D63A
BioProject PRJNA756561
SRA SRP333481

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Supplementary file Size Download File type/resource
GSE182520_RNAseq.counts.normalizedByDeseq2.txt.gz 822.4 Kb (ftp)(http) TXT
GSE182520_RNAseq.counts.rawCounts.txt.gz 395.8 Kb (ftp)(http) TXT
GSE182520_smallRNA.Final.Analysis.combined.RPM.min5.xlsx 104.2 Kb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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