|
| Status |
Public on Aug 27, 2021 |
| Title |
Human retinal organoids release extracellular vesicles that regulate gene expression in target human retinal progenitors |
| Organisms |
Homo sapiens; blank sample |
| Experiment type |
Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
Developing human retinal organoids and their EVs contain unique populations of small noncoding RNAs, including miRNA, piRNA and tRNA. The EV genetic cargo has functions correlated to retinal differentiation and development. Retinal organoid EVs educate multipotent retinal progenitor cell differentiation toward photoreceptor and ganglion cell fates.
|
| |
|
| Overall design |
Human retinal organoid EV miRNA cargo and their effect on target human retinal progenitor cells mRNA expression characterized.
|
| |
|
| Contributor(s) |
Canto-Soler MV, Redenti S |
| Citation(s) |
34702879 |
| |
| Submission date |
Aug 20, 2021 |
| Last update date |
Nov 03, 2021 |
| Contact name |
Stephen Redenti |
| E-mail(s) |
stephen.redenti@lehman.cuny.edu
|
| Phone |
6468725363
|
| Organization name |
Lehman College, CUNY
|
| Lab |
Science Hall 3402
|
| Street address |
Biology Dept. , 250 Bedford Park Blvd.
|
| City |
Bronx |
| State/province |
NY |
| ZIP/Postal code |
10468 |
| Country |
USA |
| |
|
| Platforms (3) |
| GPL15520 |
Illumina MiSeq (Homo sapiens) |
| GPL17303 |
Ion Torrent Proton (Homo sapiens) |
| GPL27039 |
Illumina MiSeq (blank sample) |
|
| Samples (21)
|
|
| Relations |
| BioProject |
PRJNA756561 |
| SRA |
SRP333481 |
Less...
More...