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Status |
Public on Oct 29, 2021 |
Title |
Expression (Gene) in the endothelial cells of the mouse male prefrontal cortex (PFC) following 10-day chronic social stress exposure [male CSDS] |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Cell-specific transcriptomic analysis were performed on PFC endothelial cells of unstressed controls (CTRL), stress-susceptible (SS) and resilient (RES) mice to identify novel genes and pathways involved in stress responses
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Overall design |
Animals were subject to 10 days of chronic social defeat stress, phenotype using a social interaction test then the brains were collected 24h later and PFC punched for magnetic-activated cell sorting and transcriptomic analyses. Genome Quebec (extracted RNA, assessed quality using the bioanalyzer, performed the Clariom S mouse assay according to the manufacturer's instructions).
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Contributor(s) |
Dion-Albert L, Lebel M, Menard C |
Citation(s) |
35013188 |
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Submission date |
Aug 24, 2021 |
Last update date |
Jan 28, 2022 |
Contact name |
Caroline Menard |
E-mail(s) |
Caroline.Menard@fmed.ulaval.ca
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Organization name |
Université Laval
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Department |
Psychiatry and Neuroscience
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Lab |
menardneurolab.com
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Street address |
CERVO Brain Research Center, 2601 de la Canardiere
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City |
Quebec City |
State/province |
QC |
ZIP/Postal code |
G1J 2G3 |
Country |
Canada |
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Platforms (1) |
GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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Samples (21)
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This SubSeries is part of SuperSeries: |
GSE173823 |
Sex-specific blood-brain barrier alterations and vascular biomarkers underlie chronic stress responses in mice and human depression. |
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Relations |
BioProject |
PRJNA757402 |