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Status |
Public on Sep 05, 2021 |
Title |
RNA-seq analysis of zip-1(jy13) mutants (ERT590) following 0.5 h and 4 h BTZ treatment |
Organism |
Caenorhabditis elegans |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Comparison of gene expression in wild-type and zip-1(jy13) mutant animals following bortezomib or DMSO (control) treatment. We report that induction of some genes upon bortezomib treatment is zip-1 dependent.
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Overall design |
Synchronized populations of N2 and zip-1(jy13) animals that were grown at 20°C for 48 h were treated with DMSO or bortezomib (BTZ) for 0.5 h or 4 h. Total RNA was isolated. 3 experimental replicates were performed.
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Contributor(s) |
Lažetić V, Wu F, Cohen LB, Reddy KC, Chang Y, Gang SS, Bhabha G, Troemel ER |
Citation(s) |
35013162 |
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Submission date |
Sep 03, 2021 |
Last update date |
Jan 28, 2022 |
Contact name |
Emily Troemel |
E-mail(s) |
etroemel@ucsd.edu
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Organization name |
University of California, San Diego
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Department |
Cell and Developmental Biology
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Lab |
Troemel
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Street address |
4202 Bonner Hall, 9500 Gilman #0349
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City |
La Jolla |
State/province |
California |
ZIP/Postal code |
92093 |
Country |
USA |
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Platforms (1) |
GPL22765 |
Illumina HiSeq 4000 (Caenorhabditis elegans) |
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Samples (24)
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Relations |
BioProject |
PRJNA760436 |
SRA |
SRP335548 |