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Series GSE183361 Query DataSets for GSE183361
Status Public on Sep 05, 2021
Title RNA-seq analysis of zip-1(jy13) mutants (ERT590) following 0.5 h and 4 h BTZ treatment
Organism Caenorhabditis elegans
Experiment type Expression profiling by high throughput sequencing
Summary Comparison of gene expression in wild-type and zip-1(jy13) mutant animals following bortezomib or DMSO (control) treatment. We report that induction of some genes upon bortezomib treatment is zip-1 dependent.
 
Overall design Synchronized populations of N2 and zip-1(jy13) animals that were grown at 20°C for 48 h were treated with DMSO or bortezomib (BTZ) for 0.5 h or 4 h. Total RNA was isolated. 3 experimental replicates were performed.
 
Contributor(s) Lažetić V, Wu F, Cohen LB, Reddy KC, Chang Y, Gang SS, Bhabha G, Troemel ER
Citation(s) 35013162
Submission date Sep 03, 2021
Last update date Jan 28, 2022
Contact name Emily Troemel
E-mail(s) etroemel@ucsd.edu
Organization name University of California, San Diego
Department Cell and Developmental Biology
Lab Troemel
Street address 4202 Bonner Hall, 9500 Gilman #0349
City La Jolla
State/province California
ZIP/Postal code 92093
Country USA
 
Platforms (1)
GPL22765 Illumina HiSeq 4000 (Caenorhabditis elegans)
Samples (24)
GSM5556274 N2_DMSO_05h_rep1_combined
GSM5556275 N2_DMSO_05h_rep2_combined
GSM5556276 N2_DMSO_05h_rep3_combined
Relations
BioProject PRJNA760436
SRA SRP335548

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE183361_Matrix_05h_limmavoom_normalized_counts.tabular.txt.gz 1.4 Mb (ftp)(http) TXT
GSE183361_Matrix_4h_limmavoom_normalized_counts.tabular.txt.gz 940.2 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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