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| Status |
Public on Oct 27, 2021 |
| Title |
Cellular heterogeneity of circulating CD4+CD8+ double positive T cells characterized by single-cell RNA sequencing |
| Organism |
Macaca fascicularis |
| Experiment type |
Expression profiling by high throughput sequencing
Other
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| Summary |
We subdivided circulating CD4+CD8+ double positive T cells, which are known to be related to various disease environments, into several subtypes through single-cell RNA sequencing, and compared gene signatures according to CD4 and CD8 protein expression levels using CD4 and CD8 antibody derived tags (feature barcode).
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| Overall design |
Heterogeneous subsets of circulating CD4+CD8+ double positive T cells were analyzed by scRNA-seq after labeling CD4 and CD8 feature barcodes, characterized their characteristic with CD4, CD8 coreceptor expresion levels.
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| Contributor(s) |
Lee JI, Choi SM |
| Citation(s) |
34880348 |
| |
| Submission date |
Sep 09, 2021 |
| Last update date |
Dec 15, 2021 |
| Contact name |
Jaeil Lee |
| E-mail(s) |
jaeil@snu.ac.kr
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| Phone |
82-2-740-8577
|
| Organization name |
Seoul National University
|
| Street address |
103 Daehak-ro, Jongno-gu
|
| City |
Seoul |
| ZIP/Postal code |
03080 |
| Country |
South Korea |
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| Platforms (1) |
| GPL24953 |
Illumina HiSeq 4000 (Macaca fascicularis) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA762084 |
| SRA |
SRP336412 |
