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| Status |
Public on Sep 11, 2022 |
| Title |
Krüppel-like factors-4 and -2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritis [ChIP-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
ChIP-seq with anti-HA tag antibody in TC28a2 cells transfected with HA-KLF4.We performed genome-wide analysis for KLF4-DNA association in TC28a2 human chondrocyte cells, to elucidate regulatory mechanisms of chondrogenic genes by KLF4.
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| Overall design |
ChIP samples obtained from TC28a2 cells transfected with a vector expressing KLF4 and HA tag (HA-KLF4) were analyzed in duplicate. We also analyzed an IgG ChIP control obtainted from HA-KLF4 transfected cells, and a ChIP control sample with anti HA-tag antibody from empty vector-transfected cells.
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| Contributor(s) |
Kawata M, Sundaresan A, Lotz MK |
| Citation(s) |
35534137, 37681413 |
| Submission date |
Sep 11, 2021 |
| Last update date |
Oct 19, 2023 |
| Contact name |
Padma Natarajan |
| E-mail(s) |
ccbb@scripps.edu
|
| Organization name |
The Scripps Research Institute
|
| Department |
CCBB
|
| Street address |
10550 N.Torrey Pines Road
|
| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92037 |
| Country |
USA |
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| Platforms (1) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE183956 |
Krüppel-like factors-4 and -2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritis |
|
| Relations |
| BioProject |
PRJNA762489 |
| SRA |
SRP336655 |
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