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Series GSE184823 Query DataSets for GSE184823
Status Public on Sep 26, 2024
Title The effect of Uphill and Downhill treadmill Running on the transcription of peripheral blood mononuclear cells in young male SD rats
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary Using Affymetrix GeneChip® Rat Genome 230 2.0 Array chip to screen the effect of Uphill and Downhill treadmill exercise on the key genes that affect bone mass in the peripheral blood mononuclear cells (PBMCs) of young male rats.
Thirty-six male Sprague-Dawley rats were randomly assigned to a control group and both running groups of uphill and downhill (n = 12). Bone mineral density (BMD), bone mineral content (BMC) and bone microstructure of the femur were measured. PBMCs were extracted and the gene expression profile of mRNA detected.Gene Ontology and KEGG pathway analysis were used.The results showed exercise mainly activated the biological processes and cellular pathways involved in immune, inflammation and osteoclast differentiation.
 
Overall design the effect of Uphill and Downhill treadmill exercise on the mRNA profiles in the peripheral blood mononuclear cells (PBMCs) of young male SD rats.
 
Contributor(s) Yang J
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Submission date Sep 27, 2021
Last update date Sep 26, 2024
Contact name jie -yong yang
E-mail(s) yangyongjie@sdpei.edu.cn
Phone 18668930520
Organization name Human Movement Science
Street address 山东省济南市世纪大道10600号
City Ji’nan ,China
ZIP/Postal code 250102
Country China
 
Platforms (1)
GPL1355 [Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Samples (3)
GSM5597821 controlgroup-C
GSM5597822 downhill treadmill running group-D
GSM5597823 uphill treadmill running group-U
Relations
BioProject PRJNA766609

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE184823_RAW.tar 7.8 Mb (http)(custom) TAR (of CEL)
GSE184823_RMA_Matrix.xlsx 17.2 Mb (ftp)(http) XLSX
Processed data included within Sample table
Processed data are available on Series record

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