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Status |
Public on Sep 26, 2024 |
Title |
The effect of Uphill and Downhill treadmill Running on the transcription of peripheral blood mononuclear cells in young male SD rats |
Organism |
Rattus norvegicus |
Experiment type |
Expression profiling by array
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Summary |
Using Affymetrix GeneChip® Rat Genome 230 2.0 Array chip to screen the effect of Uphill and Downhill treadmill exercise on the key genes that affect bone mass in the peripheral blood mononuclear cells (PBMCs) of young male rats. Thirty-six male Sprague-Dawley rats were randomly assigned to a control group and both running groups of uphill and downhill (n = 12). Bone mineral density (BMD), bone mineral content (BMC) and bone microstructure of the femur were measured. PBMCs were extracted and the gene expression profile of mRNA detected.Gene Ontology and KEGG pathway analysis were used.The results showed exercise mainly activated the biological processes and cellular pathways involved in immune, inflammation and osteoclast differentiation.
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Overall design |
the effect of Uphill and Downhill treadmill exercise on the mRNA profiles in the peripheral blood mononuclear cells (PBMCs) of young male SD rats.
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Contributor(s) |
Yang J |
Citation missing |
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Submission date |
Sep 27, 2021 |
Last update date |
Sep 26, 2024 |
Contact name |
jie -yong yang |
E-mail(s) |
yangyongjie@sdpei.edu.cn
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Phone |
18668930520
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Organization name |
Human Movement Science
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Street address |
山东省济南市世纪大道10600号
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City |
Ji’nan ,China |
ZIP/Postal code |
250102 |
Country |
China |
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Platforms (1) |
GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
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Samples (3) |
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Relations |
BioProject |
PRJNA766609 |