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| Status |
Public on Aug 10, 2022 |
| Title |
Next Generation Sequencing Facilitates Quantitative Analysis of NP1 and NP1/CRTCHA Gut Transcriptomes |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Differential expression analysis used the DESeq2 Bioconductor package, a model based on the negative binomial distribution. the estimates of dispersion and logarithmic fold changes incorporate data-driven prior distributions, Padj of genes were setted <0.05 to detect differential expressed ones.Our study represents the detailed analysis of of NP1 and NP1/CRTCHA drosophila gut transcriptomes, with biologic replicates, generated by RNA-seq technology.Transcriptome analysis indicated that the genes involved in proteasome assembly, ROS scavengers, and protein folding were highly enriched among those differentially expressed genes (DEGs) in CRTC overexpressing (CRTCOE) intestines.
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| Overall design |
Gut mRNA profiles of 3-5-day old NP1/+ and NP1/+;UASCRTCHA/+ drosophila
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| Contributor(s) |
Deng H, Yin Y |
| Citation(s) |
35933423 |
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| Submission date |
Oct 01, 2021 |
| Last update date |
Aug 10, 2022 |
| Contact name |
HANSONG DENG |
| E-mail(s) |
HDENG@TONGJI.EDU.CN
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| Phone |
+8617364161727
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| Organization name |
Tongji University
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| Street address |
RM 5O1, BLDG 1, # 817 ZHENGLI RD, YANGPU DISTRICT
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| City |
SHANGHAI1 |
| ZIP/Postal code |
200085 |
| Country |
China |
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| Platforms (1) |
| GPL13304 |
Illumina HiSeq 2000 (Drosophila melanogaster) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA767845 |
| SRA |
SRP339659 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE185159_gene_expression_CRTC.fpkm_anno.xlsx |
3.2 Mb |
(ftp)(http) |
XLSX |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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