|
| Status |
Public on Nov 29, 2011 |
| Title |
Deciphering the Wnt-dependent gene signature in colorectal cancer cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Microarray-based gene expression data were generated from RNA from Ls174T colorectal carcinoma cell lines in which Wnt-dependent transcriptional activity can be abrogated by inducible overexpression of a dominant-negative form of Tcf4 or siRNA against β-catenin.
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| |
|
| Overall design |
shRNA against β-catenin, or a dominant-negative Tcf4 transgene, were induced in Ls174T cells for 72 or 24 hours, respectively. Uninduced cells were used as a control. Three replicates per condition.
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| |
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| Contributor(s) |
Mokry M, Hatzis P, de Bruijn E, Koster J, Versteeg R, van de Wetering M, Guryev V, Clevers H, Cuppen E |
| Citation(s) |
21914722 |
| |
| Submission date |
Oct 14, 2009 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Richard Volckmann |
| E-mail(s) |
r.volckmann@amsterdamumc.nl
|
| Organization name |
Academic Medical Centre, University of Amsterdam
|
| Department |
Department of Oncogenomics
|
| Street address |
P.O. Box 22700
|
| City |
Amsterdam |
| ZIP/Postal code |
1100DE |
| Country |
Netherlands |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA121379 |
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