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Series GSE185885 Query DataSets for GSE185885
Status Public on Apr 13, 2022
Title ALKBH5 promotes tumor progression by decreasing RIG-I expression mediated by N6-methyladenosine-dependent HNRNPC binding in HNSCC [MeRIP-seq]
Organism Homo sapiens
Experiment type Methylation profiling by high throughput sequencing
Expression profiling by high throughput sequencing
Summary To determine the targets underlying ALKBH5 during head and neck squamouse cell carcinoma progression, Methylated RNA immunoprecipitation (MeRIP) with an m6A specific antibody followed by RNA sequencing (MeRIP-seq) and next generation sequencing were combined to screen the potential targets haboring m6A modificatios and mRNA level alteration after ALKBH5 knockdown in a HNSCC cell line.
 
Overall design MeRIP-seq was conducted in Cal27 cells after ALKBH5 silencing for 24 h.
 
Contributor(s) Ma H, Jin S
Citation(s) 35395767
Submission date Oct 13, 2021
Last update date Apr 13, 2022
Contact name Hailong Ma
E-mail(s) mahl21@sjtu.edu.cn
Organization name Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine
Street address Zhizaoju Rd
City Shanghai
ZIP/Postal code 200011
Country China
 
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (8)
GSM5625263 si-scramble rep 1 IP
GSM5625264 si-scramble rep 1 Input
GSM5625265 si-scramble rep 2 IP
This SubSeries is part of SuperSeries:
GSE185888 ALKBH5 promotes tumor progression by decreasing RIG-I expression mediated by N6-methyladenosine-dependent HNRNPC binding in HNSCC
Relations
BioProject PRJNA771104
SRA SRP341304

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE185885_Methylated_RNA_sites.mRNA.xlsx 5.3 Mb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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