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Series GSE186633 Query DataSets for GSE186633
Status Public on Oct 16, 2023
Title CHD1 Alters Sensitivity to Aurora Kinase A Inhibitors
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary In this study, we sought to understand the impact of CHD1 on sensitivity to Aurora A inhibitors in prostate and other cancers and underlying mechanisms
 
Overall design WT and CHD1 KO BPH1 cells were treated with DMSO or Alisertib (10μM) for 24 hours. Then, cells were lysed with TRIzol, followed by RNA extraction. Experiment was performed in triplicate. RNA-Sequencing was performed by UT MD Anderson Science Park NGS Core.
 
Contributor(s) Zhao D, Li H, Lu Y, Lin K
Citation(s) 35771632
Submission date Oct 26, 2021
Last update date Oct 16, 2023
Contact name Di Zhao
E-mail(s) dzhao2@mdanderson.org
Phone 7137455214
Organization name MD Anderson Cancer Center
Lab Zhao lab
Street address Zayed Building Z7. 4018
City Houston
State/province Tx
ZIP/Postal code 77030
Country USA
 
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (12)
GSM5658029 KO_Ali1
GSM5658030 KO_Ali2
GSM5658031 KO_Ali3
Relations
BioProject PRJNA774875
SRA SRP343288

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE186633_DESeq_counts.txt.gz 1.6 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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