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| Status |
Public on May 24, 2022 |
| Title |
Vocal learning-associated convergent evolution in mammalian regulatory elements and proteins |
| Organism |
Rousettus aegyptiacus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
This represents the first transcriptomic and epigenomic characterization of the vocalization-associated brain circuits of a non-human mammalian vocal learner (Egyptian fruit bat), yielding fundamental insights into the regulatory and molecular pathways underlying the evolution of complex vocal behavior in mammals.
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| |
|
| Overall design |
We generated ATAC-seq and RNAseq from a range of adult Egyptian fruit bat (Rousettus aegyptiacus) tissues, including 7 brain regions and 3 non-brain tissues.
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| |
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| Contributor(s) |
Wirthlin ME, Zhang X, Kaplow IM, Pfenning AR |
| Citation(s) |
38422184 |
| |
| Submission date |
Nov 03, 2021 |
| Last update date |
Sep 05, 2024 |
| Contact name |
Morgan Wirthlin |
| E-mail(s) |
mwirthlin@cmu.edu
|
| Organization name |
Carnegie Mellon University
|
| Department |
Computational Biology
|
| Lab |
Andreas Pfenning
|
| Street address |
4400 Fifth Ave
|
| City |
Pittsburgh |
| State/province |
Pennsylvania |
| ZIP/Postal code |
15213 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL30616 |
Illumina NovaSeq 6000 (Rousettus aegyptiacus) |
|
| Samples (32)
|
|
| Relations |
| BioProject |
PRJNA777475 |
| SRA |
SRP344371 |
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