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Series GSE189986 Query DataSets for GSE189986
Status Public on Feb 13, 2024
Title Short-term effects of Elastase inhibition on human islets protein phosphorylation
Organism Homo sapiens
Experiment type Protein profiling by protein array
Summary To evaluate the short-term effect of elastase inhibition using telaprevir or sivelestat or DMSO on human islets
 
Overall design Human islets (N=3) were treated for 10 or 30 minutes with DMSO, telaprevir (1 and 100 µg/ml) or sivelestat (100 µg/ml) to evaluate the changes in phosphorylation levels of proteins using the KAM-1325 phospho antibody microarray (Kinexus).
 
Contributor(s) Basile G, Kulkarni R
Citation(s) 37339634
Submission date Dec 02, 2021
Last update date Feb 14, 2024
Contact name Jonathan M Dreyfuss
Organization name Joslin Diabetes Center
Department Bioinformatics & Biostatistics Core
Street address 1 Joslin Pl
City Boston
State/province MA
ZIP/Postal code 02215
Country USA
 
Platforms (1)
GPL26730 Kinex™ KAM-1325 antibody microarray
Samples (24)
GSM5710863 Donor 1; DMSO; 10 min
GSM5710864 Donor 1; Telaprevir_Low; 10 min
GSM5710865 Donor 1; Telaprevir_High; 10 min
Relations
BioProject PRJNA785484

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE189986_RAW.tar 32.2 Mb (http)(custom) TAR (of XLSX)
Processed data included within Sample table
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