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Series GSE190313 Query DataSets for GSE190313
Status Public on Jun 07, 2023
Title Role of HNF4a in bone
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary RNAseq of osteocyte and osteoblasts enriched bone fraction from the tibiae of 6 week-old male mice with a conditional deletion of Hnf4a in osteoblasts and and WT littermates.
Overall design Hnf4αflox/+ (B6.129X1(FVB)-Hnf4αtm1.1Gonz/J) and osteocalcin-Cre (B6.FVB-Tg(BGLAP-cre)1Clem/J) mice were crossed to generate Hnf4αflox/flox (WT) and Hnf4αflox/flox-Cre (Hnf4αcKO). At 6 weeks, mice were sacrificed, and tibiae were excised, epiphyses removed and bone marrow flushed. Total RNA was isolated and submitted for RNAsequencing.
Contributor(s) David V, Martin A, Martinez Calle M
Citation(s) 37079387
Submission date Dec 06, 2021
Last update date Jun 07, 2023
Contact name Valentin David
Phone 13125034159
Organization name Northwestern University
Department Medicine
Lab David Lab
Street address 320 E Superior Street
City Chicago
State/province Illinois
ZIP/Postal code 60611
Country USA
Platforms (1)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
Samples (8)
GSM5719663 WT-rep1
GSM5719664 WT-rep2
GSM5719665 WT-rep3
BioProject PRJNA786626

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Supplementary file Size Download File type/resource
GSE190313_Processed_Data.xlsx 11.7 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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