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Series GSE190628 Query DataSets for GSE190628
Status Public on Dec 01, 2023
Title RNA-Sequencing of HepG2 cells treated with Chinese herbal medicine Pulsatilla Chinensis
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Pulsatilla chinensis (PC) is a traditional Chinese medicinewith detoxification activities. It has been used for dysentery, vaginal trichomoniasis, bacterial infections and malignant tumor treatment. Gavage administration of PC in hyperlipidemia rats for 11 weeks resulted in obviously reduced serum total cholesterol, LDL-cholesterol and ameliorated fatty liver. So we wanted to further investigate the relationship between PC and lipid metabolism related pathways or genes
Overall design Analysis used DMSO treated cell as control samples for comparison to the experimental samples treated with extracts of Chinese herbal medicine Pulsatilla Chinensis, genes expression changes were determined by RNA-Seq to determine Pulsatilla Chinensis responsive genes
Contributor(s) Wang RJ, Xie L, Feng J, Zhang XL
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Submission date Dec 10, 2021
Last update date Dec 01, 2023
Contact name ruijun wang
Phone 18518157361
Organization name Tsinghua university
Street address college of life science
City beijing
ZIP/Postal code 102206
Country China
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (6)
GSM5726813 DMSO rep1
GSM5726814 DMSO rep2
GSM5726815 DMSO rep3
This SubSeries is part of SuperSeries:
GSE190631 RNA-Sequencing of HepG2 cells and rats treated with Chinese herbal medicine Pulsatilla Chinensis
BioProject PRJNA787820

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE190628_RAW.tar 1.8 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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