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| Status |
Public on Dec 16, 2022 |
| Title |
Spatially resolved epigenomic profiling of single cells in complex tissues |
| Organism |
Homo sapiens |
| Experiment type |
Other
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| Summary |
The recent development of spatial omics enables single-cell profiling of the transcriptome and the 3D organization of the genome in a spatially resolved manner. A spatial epigenomics method would expand the repertoire of spatial omics tools and accelerate our understanding of the spatial regulation of cellular processes and tissue functions. Here, we developed an imaging approach for spatially resolved profiling of epigenetic modifications in single cells
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| Overall design |
Examination of the epigenome using single cell epigenomic methods
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| Contributor(s) |
Ang C, Lu T, Zhuang X |
| Citation(s) |
36272405 |
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| Submission date |
Dec 16, 2021 |
| Last update date |
Mar 23, 2023 |
| Contact name |
Cheen Euong Ang |
| E-mail(s) |
cang@fas.harvard.edu
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| Organization name |
Stanford University
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| Street address |
265 Campus Drive, G3145
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| City |
Stanford |
| State/province |
CA |
| ZIP/Postal code |
94305 |
| Country |
USA |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (5)
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| Relations |
| BioProject |
PRJNA789560 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE191069_Epigenomic_MERFISH_protocol.pdf |
91.6 Kb |
(ftp)(http) |
PDF |
| GSE191069_RAW.tar |
910.0 Kb |
(http)(custom) |
TAR (of NARROWPEAK) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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