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Series GSE192961 Query DataSets for GSE192961
Status Public on May 10, 2023
Title Super enhancers orchestrate osteogenesis program through navigation and initiation effects of Brd4 on Zbtb16 [ChIP-Seq]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We performed multiomic high-throughput sequencing to recapitulated the primary mechanism of mesenchymal stem cells osteogenesis. We analysed the H3K27ac ChIP-seq and RNA-seq data before and after osteogenesis, and identified super enhancers (SEs) regulated osteogenic identity genes in MSCs.
 
Overall design Examination of the H3K27ac modification in MSCs before and after osteogenesis.
 
Contributor(s) Shen H, Xie Z, Wu Y, Yu W
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Submission date Jan 03, 2022
Last update date May 12, 2023
Contact name Wenhui Yu
E-mail(s) yuwh5@mail2.sysu.edu.cn
Organization name The Eighth Affiliated Hospital of Sun Yat-sen University
Department Department of Orthopedics
Street address Shennan middle road #3025
City Shenzhen
ZIP/Postal code 518003
Country China
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (4)
GSM5769857 NC_input
GSM5769858 NC_H3K27ac
GSM5769859 OB_input
This SubSeries is part of SuperSeries:
GSE192963 Super enhancers orchestrate osteogenesis program through navigation and initiation effects of Brd4 on Zbtb16
Relations
BioProject PRJNA793901

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE192961_RAW.tar 196.6 Mb (http)(custom) TAR (of BW, TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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