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Status |
Public on Jan 19, 2022 |
Title |
Differentially expressed genes between YY1 knockdown and control cells, transfected in colorectal cancer cell line DLD-1 |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Yin Yang 1 (YY1) is a multifunctional transcription factor with critical roles in carcinogenesis and metastasis. However, its biological role and clinical impact in colorectal cancer (CRC) remain unclear. This study aimed to elucidate the oncological role of YY1 in CRC. To indentify the target genes of YY1, microarray analysis was performed on siYY1 and siControl transfected cells.
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Overall design |
DLD-1 was transfected with siControl and siYY1. After culturing for 3 days, total RNA was isolated from each cell. Differentially expressed genes in YY1 knockdown cells compared to siControl cells were analyzed.
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Contributor(s) |
Sato N |
Citation missing |
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Submission date |
Jan 18, 2022 |
Last update date |
Jan 22, 2022 |
Contact name |
Nami Sato |
Organization name |
Chiba university
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Department |
General Surgery
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Street address |
Chuo-ku, Inohana 1-8-1
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City |
Chiba city |
State/province |
Chiba purefecture |
ZIP/Postal code |
260-8677 |
Country |
Japan |
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Platforms (1) |
GPL23159 |
[Clariom_S_Human] Affymetrix Clariom S Assay, Human (Includes Pico Assay) |
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Samples (2) |
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This SubSeries is part of SuperSeries: |
GSE194120 |
Yin Yang 1 regulates ITGAV and ITGB1, contributing to better prognosis of colorectal cancer |
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Relations |
BioProject |
PRJNA798456 |