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Series GSE19475 Query DataSets for GSE19475
Status Public on Dec 16, 2009
Title Gene expression data from infants (<1 year of age) diagnosed with Acute Lymphoblastic Leukemia (ALL)
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Acute Lymphoblastic Leukemia (ALL) in infants (<1 year) is characterized by a poor prognosis and a high incidence of MLL translocations. Several studies demonstrated the unique gene expression profile associated with MLL-rearranged ALL, but generally small cohorts were analyzed as uniform patient groups regardless of the type of MLL translocation, while the analysis of translocation-negative infant ALL remained unacknowledged.
 
Overall design We generated and analyzed primary infant ALL expression profiles (n=73) typified by translocations t(4;11), t(11;19) and t(9;11), or the absence of MLL translocations, in order to study translocation-specific gene expression between the different genetic subtypes of infant ALL.
 
Contributor(s) Stam RW, Pieters R
Citation(s) 20032505, 21116279, 22015773, 25793396, 23403319, 24736461, 28943635
Submission date Dec 15, 2009
Last update date Mar 13, 2020
Contact name Ronald Stam
E-mail(s) r.stam@erasmusmc.nl
Organization name Erasmus MC - Sophia Children's Hospital
Street address Dr. Molewaterplein 60
City Rotterdam
ZIP/Postal code 3015 GE
Country Netherlands
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (73)
GSM485250 Infant ALL MLL-AF4 positive sample 1
GSM485251 Infant ALL MLL-AF4 positive sample 2
GSM485252 Infant ALL MLL-AF4 positive sample 3
Relations
BioProject PRJNA122261

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE19475_RAW.tar 362.7 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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