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Status |
Public on Feb 09, 2022 |
Title |
miR-4730 suppresses progression of hepatocellular carcinoma by targeting high mobility group A1 pathway |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Expression of miR-4730 in hepatocellular carcinoma suppresses tumor progression, and might be a prognostic marker or a therapeutic target of miRNA-based therapies.
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Overall design |
Total RNA of Li-7 and HEP-G2 cells were extracted using an miRNeasy Mini Kit (Qiagen; Hamburg, GErmany). Real-time quantitative PCR (The Step One plus Real-Time PCR System; Applied Biosystems, Foster City, CA) and TaqMan Gene Expression Assays (Applied Biosystems) were employed. We compared the differences in gene expression between negative control and miR-4730 mimic transfection in Li-7 and HEP-G2 cells using Microarray assay.
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Contributor(s) |
Konishi H, Furuke H, Arita T, Kataoka S, Shibamoto J, Takabatake K, Takaki W, Shimizu H, Yamamoto Y, Morimura R, Komatsu S, Shiozaki A, Ikoma H, Otsuji E |
Citation(s) |
35485281 |
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Submission date |
Feb 07, 2022 |
Last update date |
May 11, 2022 |
Contact name |
Hirotaka Furuke |
E-mail(s) |
hfuruke@koto.kpu-m.ac.jp
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Phone |
09097129067
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Organization name |
Kyoto Prefectural University of Medicine
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Department |
Division of digestive surgery
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Street address |
465 Kajii-cho, Kamigyo-ku, Kyoto, 60285
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City |
Kyoto |
State/province |
Japan |
ZIP/Postal code |
602-8566 |
Country |
Japan |
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Platforms (1) |
GPL23159 |
[Clariom_S_Human] Affymetrix Clariom S Assay, Human (Includes Pico Assay) |
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Samples (4)
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Relations |
BioProject |
PRJNA804117 |
Supplementary file |
Size |
Download |
File type/resource |
GSE196261_RAW.tar |
5.0 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
Processed data included within Sample table |
Processed data are available on Series record |
Processed data provided as supplementary file |
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