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Series GSE197382 Query DataSets for GSE197382
Status Public on Nov 08, 2023
Title 5' UTR-dependent m6A methylation regulates aging and circadian rhythms in Drosophila [RNA-seq whole]
Organism Drosophila melanogaster
Experiment type Expression profiling by high throughput sequencing
Summary To evoke further attention to the potential hazard of increasingly accumulative blue light exposure, we construct a series of in vivo Drosophila models employed for multi-omics analyses. This project includes the RNA-seq data of w1118 F1 generation male adult whole flies.
 
Overall design Briefly, we colonized Drosophila melanogaster w1118 under the photoperiodic cycles of 12 h low-intensity blue light exposure: 12 h darkness (BD) and consistent darkness (DD) until 10- (namely BD10 and DD10) and 25-day-old (namely BD25 and DD25) after eclosion, respectively. We then performed polyadenylated (poly-A) MeRIP-seq and untargeted metabolome analysis for the male adult whole flies, and performed poly-A RNA-seq for the male adult heads and the 3-day-old male adult whole flies grew from the earlier eggs as the F1 generation (namely BD8F1, BD23F1, DD8F1, and DD23F1, respectively) for assessing the influences of parental photoperiods and natural aging.
 
Contributor(s) Huang J, Zhou F, Wang X
Citation(s) 38059264
Submission date Feb 24, 2022
Last update date Dec 14, 2023
Contact name Xiaoyun Wang
E-mail(s) wang_xiaoyun@gibh.ac.cn
Organization name Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
Department Infection and Immunity
Street address 190 Kaiyuan Avenue, Huangpu
City Guangzhou
State/province Guangdong
ZIP/Postal code 510530
Country China
 
Platforms (1)
GPL25244 Illumina NovaSeq 6000 (Drosophila melanogaster)
Samples (12)
GSM5915391 Whole_RNA_BD8F1-1
GSM5915392 Whole_RNA_BD8F1-2
GSM5915393 Whole_RNA_BD8F1-3
This SubSeries is part of SuperSeries:
GSE197397 5' UTR-dependent m6A methylation regulates aging and circadian rhythms in Drosophila
Relations
BioProject PRJNA810060

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE197382_Whole_RNA_F1_Count.txt.gz 365.7 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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