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| Status |
Public on Dec 31, 2010 |
| Title |
Gene Expression Profiling Data of African Malaria Vector Anopheles gambiae Aging |
| Platform organisms |
Plasmodium falciparum; Anopheles gambiae |
| Sample organism |
Anopheles gambiae |
| Experiment type |
Expression profiling by array
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| Summary |
Senescence is a biological phenomenon experienced by all living eukaryote organisms. Genome-wide gene expression associated with aging has been explored in model organisms such as Drosophila melanogaster and Caenorhabditis elegans, but this has not been well understood in African malaria vector, Anopheles gambiae. Gene expression profiling using DNA microarray allows for simultaneous study of changes in mRNA levels for thousands of genes. This study examined genome-wide gene expression during aging process in An. gambiae. The influence of blood feeding on gene expression was also examined. The data can be used to further our understanding of mosquito senescence and identify biomarkers for mosquito age grading.
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| Overall design |
Transcriptional profiles of Anopheles gambiae female mosquitoes were determined at 1, 4, 10, 19 and 28 days post adult eclosion. Additionally mosquitoes that had access to blood meals were compared to those that were maintained with access to only water and sugar.
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| Contributor(s) |
Wang M, Marinotti O, Jame AA, Walker E, Yan G |
| Citation(s) |
20967211 |
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| Submission date |
Jan 06, 2010 |
| Last update date |
Jan 24, 2013 |
| Contact name |
Mei-Hui Wang |
| E-mail(s) |
meihuiw@uci.edu
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| Phone |
949-824-0249
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| Fax |
949-824-0249
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| Organization name |
UC irvine
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| Street address |
3501B Hewitt Hall UCI
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| City |
Irvine |
| State/province |
CA |
| ZIP/Postal code |
92697 |
| Country |
USA |
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| Platforms (1) |
| GPL1321 |
[Plasmodium_Anopheles] Affymetrix Plasmodium/Anopheles Genome Array |
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| Samples (31)
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| GSM493444 |
1 day old, Non blood feed, biological rep1 |
| GSM493445 |
1 day old, Non blood feed, biological rep2 |
| GSM493446 |
1 day old, Non blood feed, biological rep3 |
| GSM493447 |
1 day old, Non blood feed, biological rep4 |
| GSM493448 |
4 day old, Non blood feed, biological rep1 |
| GSM493449 |
4 day old, Non blood feed, biological rep2 |
| GSM493450 |
4 day old, Non blood feed, biological rep3 |
| GSM493451 |
4 day old, Non blood feed, biological rep4 |
| GSM493452 |
10 day old, Non blood feed, biological rep1 |
| GSM493453 |
10 day old, Non blood feed, biological rep2 |
| GSM493454 |
10 day old, Non blood feed, biological rep3 |
| GSM493455 |
10 day old, Non blood feed, biological rep4 |
| GSM493456 |
19 day old, Non blood feed, biological rep1 |
| GSM493457 |
19 day old, Non blood feed, biological rep2 |
| GSM493458 |
19 day old, Non blood feed, biological rep3 |
| GSM493459 |
19 day old, Non blood feed, biological rep4 |
| GSM493460 |
28 day old, Non blood feed, biological rep1 |
| GSM493461 |
28 day old, Non blood feed, biological rep2 |
| GSM493462 |
28 day old, Non blood feed, biological rep3 |
| GSM493463 |
10 day old, blood feed, biological rep1 |
| GSM493464 |
10 day old, blood feed, biological rep2 |
| GSM493465 |
10 day old, blood feed, biological rep3 |
| GSM493466 |
10 day old, blood feed, biological rep4 |
| GSM493467 |
19 day old, blood feed, biological rep1 |
| GSM493468 |
19 day old, blood feed, biological rep2 |
| GSM493469 |
19 day old, blood feed, biological rep3 |
| GSM493470 |
19 day old, blood feed, biological rep4 |
| GSM493471 |
28 day old, blood feed, biological rep1 |
| GSM493472 |
28 day old, blood feed, biological rep2 |
| GSM493473 |
28 day old, blood feed, biological rep3 |
| GSM493474 |
28 day old, blood feed, biological rep4 |
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| Relations |
| BioProject |
PRJNA121837 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE19756_RAW.tar |
69.5 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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