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Series GSE19756 Query DataSets for GSE19756
Status Public on Dec 31, 2010
Title Gene Expression Profiling Data of African Malaria Vector Anopheles gambiae Aging
Platform organisms Plasmodium falciparum; Anopheles gambiae
Sample organism Anopheles gambiae
Experiment type Expression profiling by array
Summary Senescence is a biological phenomenon experienced by all living eukaryote organisms. Genome-wide gene expression associated with aging has been explored in model organisms such as Drosophila melanogaster and Caenorhabditis elegans, but this has not been well understood in African malaria vector, Anopheles gambiae. Gene expression profiling using DNA microarray allows for simultaneous study of changes in mRNA levels for thousands of genes. This study examined genome-wide gene expression during aging process in An. gambiae. The influence of blood feeding on gene expression was also examined. The data can be used to further our understanding of mosquito senescence and identify biomarkers for mosquito age grading.
Overall design Transcriptional profiles of Anopheles gambiae female mosquitoes were determined at 1, 4, 10, 19 and 28 days post adult eclosion. Additionally mosquitoes that had access to blood meals were compared to those that were maintained with access to only water and sugar.
Contributor(s) Wang M, Marinotti O, Jame AA, Walker E, Yan G
Citation(s) 20967211
Submission date Jan 06, 2010
Last update date Jan 24, 2013
Contact name Mei-Hui Wang
Phone 949-824-0249
Fax 949-824-0249
Organization name UC irvine
Street address 3501B Hewitt Hall UCI
City Irvine
State/province CA
ZIP/Postal code 92697
Country USA
Platforms (1)
GPL1321 [Plasmodium_Anopheles] Affymetrix Plasmodium/Anopheles Genome Array
Samples (31)
GSM493444 1 day old, Non blood feed, biological rep1
GSM493445 1 day old, Non blood feed, biological rep2
GSM493446 1 day old, Non blood feed, biological rep3
BioProject PRJNA121837

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Supplementary file Size Download File type/resource
GSE19756_RAW.tar 69.5 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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