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| Status |
Public on Aug 01, 2022 |
| Title |
An ancestral Wnt-Brachyury feedback loop and vertebrate-specific recruitment of mesoderm-determining target genes revealed by comparative Brachyury target screens |
| Organism |
Strongylocentrotus purpuratus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Transcription factor brachyury plays a key role during mesoderm development in vertebrates. In this study we study study the effect of this transcription factor in the purple sea urchin S. purpuratus.
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| Overall design |
Brachyury binding sites were identified with ChIP-seq and effect of brachyury binding on gene expression was studied with RNA-seq.
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| Contributor(s) |
Andrikou C, Voronov D, Dnyansagar R, Schwaiger M, Paganos P, Technau U, Arnone M |
| Citation(s) |
36396969 |
| BioProject |
PRJNA756953 |
| Submission date |
Mar 10, 2022 |
| Last update date |
Nov 26, 2022 |
| Contact name |
Maria Ina Arnone |
| E-mail(s) |
miarnone@szn.it
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| Organization name |
Stazione Zoologica Anton Dohrn
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| Department |
Biology and Evolution of Marine Organisms
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| Street address |
Villa Comunale 1
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| City |
Napoli |
| State/province |
NA |
| ZIP/Postal code |
80121 |
| Country |
Italy |
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| Platforms (1) |
| GPL20965 |
Illumina HiSeq 2500 (Strongylocentrotus purpuratus) |
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| Samples (10)
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