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Series GSE198746 Query DataSets for GSE198746
Status Public on Sep 17, 2022
Title Dose Response Transcriptional Profiling of Plasmodium falciparum 3D7 and Dd2 strains treated with chloroquine (CQ), MK-4815, and mefloquine (MFQ)
Organism Plasmodium falciparum
Experiment type Expression profiling by array
Summary Gene expression changes of drug treated trophozoites of P. falciparum 3D7 and Dd2 strains (approx 26-32 HPI)
 
Overall design For each antimalarial, trophozoites were treated with 9 different concentrations of CQ, MK-4815, and MFQ (4-fold dilutions) for 6 hours. Three technical replicates of untreated control were included in each bioreplicate experiment
 
Contributor(s) Wirjanata G, Binte Zulkifli NE, Boentoro J, Bozdech Z
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Mar 16, 2022
Last update date Sep 19, 2022
Contact name Zbynek Bozdech
E-mail(s) zbozdech@ntu.edu.sg
Phone 63162925
Organization name Nanyang Technological University
Street address 50 Nanyang Avenue
City Singapore
State/province Singapore
ZIP/Postal code 639798
Country Singapore
 
Platforms (1)
GPL18893 ZB/SBS-NTU Plasmodium falciparum 3D7 11.4K v2
Samples (143)
GSM5956096 Transcriptome of P. falciparum 3D7 treated with 0.2 nM CQ for 6 hours. Bioreplicate 1
GSM5956097 Transcriptome of P. falciparum 3D7 treated with 0.6 nM CQ for 6 hours. Bioreplicate 1
GSM5956098 Transcriptome of P. falciparum 3D7 treated with 10000 nM CQ for 6 hours. Bioreplicate 1
Relations
BioProject PRJNA816720

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE198746_3D7_CQ_B1.txt.gz 742.2 Kb (ftp)(http) TXT
GSE198746_3D7_CQ_B2.txt.gz 745.8 Kb (ftp)(http) TXT
GSE198746_3D7_MFQ_B1.txt.gz 750.9 Kb (ftp)(http) TXT
GSE198746_3D7_MFQ_B2.txt.gz 741.2 Kb (ftp)(http) TXT
GSE198746_3D7_MK4815_B1.txt.gz 761.0 Kb (ftp)(http) TXT
GSE198746_3D7_MK4815_B2.txt.gz 761.2 Kb (ftp)(http) TXT
GSE198746_3D7_PRQ_B1.txt.gz 733.1 Kb (ftp)(http) TXT
GSE198746_3D7_PRQ_B2.txt.gz 671.7 Kb (ftp)(http) TXT
GSE198746_Dd2_CQ_B1.txt.gz 760.6 Kb (ftp)(http) TXT
GSE198746_Dd2_CQ_B2.txt.gz 742.8 Kb (ftp)(http) TXT
GSE198746_Dd2_MK4815_B1.txt.gz 781.4 Kb (ftp)(http) TXT
GSE198746_Dd2_MK4815_B2.txt.gz 763.1 Kb (ftp)(http) TXT
GSE198746_RAW.tar 176.6 Mb (http)(custom) TAR (of GPR)
Processed data are available on Series record

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