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Series GSE199276 Query DataSets for GSE199276
Status Public on Mar 13, 2023
Title Murine N4 Ube3am-/p+ hippocampus: Antagomir-134 vs Scramble (control)
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Transcriptional profiling of N4 Ube3am-/p+ mice ipsilateral hippocampi at 24h after the last audiogenic stimulus (at postnatal day 27; out of three stimulus) of mice pre-treated with either scramble or antagomir-134 (Ant-134; 0.5 nmol; ICV).
 
Overall design Two-condition experiment, Scramble (control) vs Antagomir-134. Biological replicates: 4 scramble (controls) and 5 antagomir-134. Each biological replicate is the homogeneate of one ipsilateral hippocampus of the respective treated mouse. P21 mice received an ICV injection of scramble or Ant-134. At P22 24 hours later, they were subjected to an audiogenic seizure. This seizure was repeated at P24 and P26. At 24h later, brains were removed and microdissected for transcriptome analysis.
 
Contributor(s) Henshall D, Ruedell Reschke C, Campbell A, Sanfeliu A, Thanh Nguyen N
Citation(s) 35592499
Submission date Mar 23, 2022
Last update date Mar 14, 2023
Contact name Albert Sanfeliu
E-mail(s) albertsanfeliu@rcsi.ie
Organization name Royal College of Surgeons in Ireland
Street address 123 St. Stephen's Green
City Dublin
ZIP/Postal code D02 YN77
Country Ireland
 
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (9)
GSM5968616 Antagomir-134-treated Sample 1
GSM5968617 Antagomir-134-treated Sample 2
GSM5968618 Antagomir-134-treated Sample 3
Relations
BioProject PRJNA819106

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE199276_gene_FPKM.csv.gz 3.4 Mb (ftp)(http) CSV
GSE199276_gene_FPKM.xlsx 9.4 Mb (ftp)(http) XLSX
GSE199276_gene_count.csv.gz 2.3 Mb (ftp)(http) CSV
GSE199276_gene_count.xlsx 7.0 Mb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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