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Status |
Public on Mar 30, 2022 |
Title |
RNA-seq in H1299 cell lines |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Purpose: The goals of this study are to investigate the primary biological process of HNRNPC. Methods: Briefly, samples (H1299 cells transfected with control or HNRNPC shRNA) were used to extract total RNAs for quality control and RNA-seq loading samples. RNA-seq was performed as DGE on an Illumia HiSeq platform and 50 bp paired-end reads were generated (BGI Co. Ltd.). Results: RNA-seq in H1299 cell lines revealed that HNRNPC mainly regulated cell growth, cell migration, extracellular matrix organization, angiogenesis, collagen fibril organization, and T cell mediated cytotoxicity. Conclusions: HNRNPC mainly regulated cell growth, cell migration, extracellular matrix organization, angiogenesis, collagen fibril organization, and T cell mediated cytotoxicity.
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Overall design |
mRNA profiles of H1299 HNRNPC shNC cells and H1299 HNRNPC knockdown cells
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Contributor(s) |
Gu Z |
Citation(s) |
- Gu Z, Yang Y, Ma Q, Wang H et al. HNRNPC, a predictor of prognosis and immunotherapy response based on bioinformatics analysis, is related to proliferation and invasion of NSCLC cells. Respir Res 2022 Dec 19;23(1):362. PMID: 36536402
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Submission date |
Mar 26, 2022 |
Last update date |
Jan 06, 2023 |
Contact name |
zhuoyu gu |
E-mail(s) |
guzhuoyu@hotmail.com
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Organization name |
First Affiliated Hospital of Zhengzhou University
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Street address |
No. 50, Jianshe East Road, Erqi District
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City |
Zhengzhou |
State/province |
China |
ZIP/Postal code |
450052 |
Country |
China |
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Platforms (1) |
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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Samples (6)
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Relations |
BioProject |
PRJNA820274 |
Supplementary file |
Size |
Download |
File type/resource |
GSE199483_gene_diff.txt.gz |
126.6 Kb |
(ftp)(http) |
TXT |
GSE199483_gene_expression.txt.gz |
117.6 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
Raw data are available in SRA |
Processed data are available on Series record |
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