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Status |
Public on Jun 07, 2024 |
Title |
Gene expression data for 637 human primary breast tumors with recurrence, ER/PR/HER2 status, and overall survival |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
We performed gene set enrichment and differential expression analysis to identify biological pathways associated with locoregional recurrence in primary breast tumors. A custom Affymetrix microarray genechip was used to assess the gene expression of each tumor sample.
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Overall design |
From a prospective tissue collection protocol representing one academic and two community hospitals, we identified 637 consecutively-treated women with primary breast tumors of invasive ductal or invasive lobular histology. Profiling of RNA extracted from tumor samples was performed with Affymetrix microarrays. Clinical variables include patient age, race, staging information, receptor status, primary surgery type, radiotherapy, and chemotherapy, while outcomes include time to locoregional recurrence and overall survival.
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Contributor(s) |
Dongliang D, Figura NB, Mills MN, Purcell JD, Grass GD, Ahmed KA, Blumencranz PW, Allen K, Laronga C, Torres-Roca JF, Thapa R, Fridley B, Wilson C, Eschrich SA, Welsh EA, Harrison LB, Robinson TJ, Diaz R |
Citation missing |
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Submission date |
Mar 28, 2022 |
Last update date |
Jun 08, 2024 |
Contact name |
Eric Welsh |
E-mail(s) |
eric.welsh@moffitt.org
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Organization name |
H Lee Moffitt Cancer Center
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Department |
Biostatistics and Bioinformatics
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Street address |
12902 Magnolia Dr
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City |
Tampa |
State/province |
FL |
ZIP/Postal code |
33612 |
Country |
USA |
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Platforms (1) |
GPL15048 |
Rosetta/Merck Human RSTA Custom Affymetrix 2.0 microarray [HuRSTA_2a520709.CDF] |
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Samples (637)
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Relations |
BioProject |
PRJNA820880 |
Supplementary file |
Size |
Download |
File type/resource |
GSE199633_RAW.tar |
3.0 Gb |
(http)(custom) |
TAR (of CEL) |
Processed data included within Sample table |
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