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Series GSE199791 Query DataSets for GSE199791
Status Public on Oct 28, 2022
Title The hallmarks of circRNA expression throughout the circadian cycle.
Organism Mus musculus
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary Circular RNAs (circRNAs) are a large class of highly stable RNA molecules with abundant expression in blood and different brain regions. CircRNA deregulation has been linked to psychiatric, neurodegenerative and neurodevelopmental disorders. Many of these brain conditions occur in parallel or arguably due to aberrant wake/sleep cycle, which is why it is necessary study circRNA expression in the context of circadian rhythm. Here we study the hallmarks of circRNA expression in different brain regions and identify potential regulators of synaptic signaling and light entrainment.
 
Overall design The hippocampus and frontal cortex were investigated during 6 different time points of the 24 hour light-dark cycle: ZT1 (07:00), ZT5 (11:00), ZT9 (15:00), ZT13 (19:00), ZT17 (23:00), ZT21 (03:00). Each group consists of 3 biological replicates. Overall (2 tissues * 6 time points * 3 replicates =) 36 samples
 
Contributor(s) Ivanov A, Mattei D, Meyer U, Beule D
Citation(s) 36293208
Submission date Mar 30, 2022
Last update date Nov 02, 2022
Contact name Andranik Ivanov
E-mail(s) andranik.ivanov@charite.de
Organization name Berlin Institute of Health
Department Core Unit Bioinformatics
Street address Chariteplatz 1
City Berlin
ZIP/Postal code 10117
Country Germany
 
Platforms (1)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
Samples (36)
GSM5984319 Frontal cortex 03:00 repl. 1
GSM5984320 Frontal cortex 03:00 repl. 2
GSM5984321 Frontal cortex 03:00 repl. 3
Relations
BioProject PRJNA821500

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Supplementary file Size Download File type/resource
GSE199791_circRNAs_cortex.tsv.gz 248.5 Kb (ftp)(http) TSV
GSE199791_circRNAs_hippocampus.tsv.gz 298.0 Kb (ftp)(http) TSV
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Raw data are available in SRA
Processed data are available on Series record

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