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Series GSE199885 Query DataSets for GSE199885
Status Public on Mar 16, 2023
Title Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Methylation profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary This SuperSeries is composed of the SubSeries listed below.
 
Overall design RNA-seq (23 samples), WGBS (4 samples), ChIP-seq (23 samples) and single-cell multiome (6 samples) of mouse cortex at 7 days or 10 weeks with H3f3a G34R/V/W histone substitutions.
 
Citation(s) 36931244
Submission date Mar 31, 2022
Last update date Jun 19, 2023
Contact name Claudia L Kleinman
E-mail(s) claudia.kleinman@mcgill.ca
Phone 514-340-8222 25139
Organization name Lady Davis Institute for Medical Research
Department Human Genetics
Street address 3999 Côte Ste-Catherine Road
City Montréal
State/province Québec
ZIP/Postal code H3T 1E2
Country Canada
 
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (62)
GSM5990179 M-2427_WT_10W_crx_RNA
GSM5990180 M-2428_G34R_10W_crx_RNA
GSM5990181 M-2492_WT_10W_crx_RNA
This SuperSeries is composed of the following SubSeries:
GSE199882 Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration [RNA-seq]
GSE199883 Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration [WGBS]
GSE199884 Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration [ChIP-seq]
Relations
BioProject PRJNA821884

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE199885_RAW.tar 66.3 Gb (http)(custom) TAR (of BW, MTX, TSV)
SRA Run SelectorHelp

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