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| Status |
Public on Apr 04, 2022 |
| Title |
Genetic Loci and Metabolic States Associated With Murine Epigenetic Aging |
| Platform organisms |
Homo sapiens; Mus musculus; Rattus norvegicus |
| Sample organism |
Mus musculus |
| Experiment type |
Methylation profiling by array
|
| Summary |
DNA methylation measured in mice belonging to the BXD Family using the HorvathMammalMethylChip40
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| Overall design |
Liver DNAm data is from 321 female and 18 male belonging to 45 members of the BXD Family, including both parental strains and F1 hybrids. Age ranged from 5.6 to 33.4 months. Mice were all weaned onto a normal chow (control diet; CD) and a balanced subset of cases were then randomly assigned to high fat diet (HFD)
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| Contributor(s) |
Mozhui K, Horvath S |
| Citation(s) |
35389339, 37691384 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R21 AG055841 |
DNA methylation and gene expression study of aging and lifespan differences |
UNIVERSITY OF TENNESSEE HEALTH SCI CTR |
Khyobeni Mozhui |
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| |
| Submission date |
Apr 01, 2022 |
| Last update date |
Sep 20, 2023 |
| Contact name |
Khyobeni Mozhui |
| E-mail(s) |
kmozhui@uthsc.edu
|
| Organization name |
University of Tennessee Health Science Center
|
| Department |
Preventive Medicine
|
| Street address |
66 N. Pauline Street, #631
|
| City |
Memphis |
| State/province |
TN |
| ZIP/Postal code |
38163 |
| Country |
USA |
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| Platforms (1) |
| GPL28271 |
Illumina HorvathMammalianMethylChip40 BeadChip |
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| Samples (339)
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| Relations |
| BioProject |
PRJNA822397 |
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