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| Status |
Public on Jun 29, 2022 |
| Title |
PI3K-mediated crosstalk between angiopoietin and vascular endothelial growth factor C signaling pathways is required for lymphangiogenesis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The aim of the study was to invetigate the crosstalk between VEGF-C/VEGFR3 and Ang2/Tie pathway
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| |
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| Overall design |
ScRNA sequence analysis contains two experiments.In first experiment, lymphatic endothelial cells from Tie1 and Tie1;Tie2 deleted lymphatic endothelial cell. The control for deletion experiments were Tamoxifen treated littermate controls, and the deleted sample had Prox1-CreERT2.
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| Contributor(s) |
Jha S, Korhonen EA, Alitalo K, Murtomaki A, Mäkinen T, Stritt S |
| Citation(s) |
35763346 |
| |
| Submission date |
May 13, 2022 |
| Last update date |
Jan 14, 2023 |
| Contact name |
Sawan KUMAR Jha |
| E-mail(s) |
jhaa.sawan@gmail.com
|
| Phone |
+16507208064
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| Organization name |
University of Helsinki
|
| Department |
Research Program Unit
|
| Street address |
Haartm
|
| City |
Helsinki |
| State/province |
Haartmaninkatu 8 |
| ZIP/Postal code |
00290 |
| Country |
Finland |
| |
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| Platforms (2) |
| GPL21493 |
Illumina HiSeq 3000 (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA838619 |
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