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| Status |
Public on May 21, 2022 |
| Title |
Network Dynamics of the Immune System decodes Asthma Endotypes |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
The ‘Genetic Epidemiology of Asthma in Costa Rica’ is a family-based cross-sectional cohort ascertained between February 2001 and August 2008 on a Hispanic population isolate from the Central Valley of Costa Rica. The study recruited children between 6 to 14 years of age with moderate persistent asthma.
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| Overall design |
GACR subjects were recruited by identifying an asthma proband from the records of the Children's Hospital of San Juan, Costa Rica. A total of 1,165 children with asthma were enrolled in the original study with written parental and participant consent. All children completed a protocol at enrollment, including questionnaires, assessment of airway responsiveness to methacholine, spirometry conducted with Survey Tach Spirometer, and collection of blood when children were not exacerbated.
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| Contributor(s) |
Fangal VD, Weiss ST, Glass K, Lasky-Su J, Begum S, Hecker J, Sonawane A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| P01 HL132825 |
Systems Biology of Airway Disease |
BRIGHAM AND WOMEN'S HOSPITAL |
SCOTT T WEISS |
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| Submission date |
May 20, 2022 |
| Last update date |
Aug 04, 2022 |
| Contact name |
Vrushali Dipak Fangal |
| E-mail(s) |
vrushali.fangal@channing.harvard.edu
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| Organization name |
Harvard Medical School
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| Department |
Brigham and Women's Hospital
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| Lab |
Channing Division of Network Medicine
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| Street address |
181 Longwood Avenue
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| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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| Samples (321)
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| Relations |
| BioProject |
PRJNA840931 |
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