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Status |
Public on Jul 19, 2010 |
Title |
global gene expression profiles in primary human hepatocytes exposed to phytochemicals |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
|
Summary |
Primary human hepatocytes were treated with 2 non-cytotoxic concentrations of sulforaphane (SFN; 10 and 50 uM) phenethyl isothiocyante (PEITC; 10 and 25 uM), 3,3'-diindolylmethane (DIM; 10 and 50 uM), or one concentration of oltipraz (OPZ; 30 uM) for 48 hours. Given the considerable heterogeneity of the human population, it was essential that each experiment was performed with hepatocytes from the same liver, i.e. each liver served as its own control. Each treatment was performed on three batches of human hepatocytes, each derived from a separate liver.
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Overall design |
32 arrays, 8 experimental groups.
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Contributor(s) |
Beyer RP, Bammler TM |
Citation(s) |
20442190 |
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Submission date |
Feb 22, 2010 |
Last update date |
Sep 05, 2017 |
Contact name |
James William MacDonald |
E-mail(s) |
jmacdon@uw.edu
|
Organization name |
University of Washington
|
Department |
Environmental and Occupational Health Sciences
|
Street address |
4225 Roosevelt Way NE
|
City |
Seattle |
State/province |
WA |
ZIP/Postal code |
98105-6099 |
Country |
USA |
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Platforms (1) |
GPL1313 |
Amersham BioSciences CodeLinkTM Uniset Human 20K I Bioarray |
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Samples (32)
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Relations |
BioProject |
PRJNA125165 |