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| Status |
Public on Mar 03, 2023 |
| Title |
Transcriptomic regulation of acidic biofilms by Candida albicans Sfl1 |
| Organism |
Candida albicans |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcriptional profiling of Candida albicans cells grown under planktonic and biofilm-inducing conditions, comparing SN76 and sfl1Δ/sfl1Δ strains. Goal was to study the effect of SFL1 deletion on the transcriptomic profile of C. albicans planktonic and biofilm cells under acidic conditions, in order to reveal the function of the Sfl1 transcription factor in C. albicans biofilm development.
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| Overall design |
Candida albicans sfl1Δ and SN76 strains were cultivated in RPMI at pH 4 for 24 h under planktonic and biofilm-inducing conditions, and then the RNA was extracted from the cells and hybridised in a species-specific DNA microarray for C. albicans (sfl1Δ/sfl1Δvs. SN76)
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| Web link |
https://linkinghub.elsevier.com/retrieve/pii/S0300-9084(23)00011-1
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| Contributor(s) |
Gonçalves BF, Barbosa A, Soares AR, Henriques M, Silva S |
| Citation(s) |
36669724 |
| |
| Submission date |
Jun 15, 2022 |
| Last update date |
Mar 05, 2023 |
| Contact name |
Ana Soares |
| E-mail(s) |
ana.r.soares@ua.pt
|
| Organization name |
University of Aveiro
|
| Street address |
Campus de Santiago
|
| City |
Aveiro |
| ZIP/Postal code |
3810 |
| Country |
Portugal |
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| Platforms (1) |
| GPL22275 |
Agilent-065138 8x15k C. albicans assembly 21 [Probe name version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA849612 |
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