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| Status |
Public on May 27, 2024 |
| Title |
Effect of KHSRP acetylation on gene expression in LNCaP cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
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| Summary |
We established LNCaP cells in wihch KHSRP was knocked down along with LNCaP cells with silenced KHSRP and re-introduced HA-tagged KHSRP-WT/K205R.RNA-seq was carried out in the stable LNCaP cell lines to determine the underlying mechanism of KHSRP acetylation in PCa tumorigenesis.
We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different cells.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for LNCaP control cells and LNCaP KD cells(shKHSRP) and comparative gene expression profiling analysis of RNA-seq data for LNCaP WT cells (sh-KHSRP-re-introduced-KHSRP-WT) and LNCaP K205R cells (sh-KHSRP-re-introduced-KHSRP-K205R)
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| Contributor(s) |
Yuan H, Xu M, Cai R |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jun 20, 2022 |
| Last update date |
May 27, 2024 |
| Contact name |
Renjie Cai |
| E-mail(s) |
renjiecaichn@126.com
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| Organization name |
Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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| Department |
Department of Oncology
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| Street address |
280 Mohe Road, Baoshan District
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| City |
Shanghai |
| ZIP/Postal code |
201900 |
| Country |
China |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA851059 |
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