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Series GSE206486 Query DataSets for GSE206486
Status Public on May 27, 2024
Title Effect of KHSRP acetylation on gene expression in LNCaP cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
Summary We established LNCaP cells in wihch KHSRP was knocked down along with LNCaP cells with silenced KHSRP and re-introduced HA-tagged KHSRP-WT/K205R.RNA-seq was carried out in the stable LNCaP cell lines to determine the underlying mechanism of KHSRP acetylation in PCa tumorigenesis.
We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different cells.
Overall design Comparative gene expression profiling analysis of RNA-seq data for LNCaP control cells and LNCaP KD cells(shKHSRP) and comparative gene expression profiling analysis of RNA-seq data for LNCaP WT cells (sh-KHSRP-re-introduced-KHSRP-WT) and LNCaP K205R cells (sh-KHSRP-re-introduced-KHSRP-K205R)
Contributor(s) Yuan H, Xu M, Cai R
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Submission date Jun 20, 2022
Last update date May 27, 2024
Contact name Renjie Cai
Organization name Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Department Department of Oncology
Street address 280 Mohe Road, Baoshan District
City Shanghai
ZIP/Postal code 201900
Country China
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (24)
GSM6255224 LNCaPsh_UTR_1
GSM6255225 LNCaPsh_UTR_2
GSM6255226 LNCaPsh_UTR_3
BioProject PRJNA851059

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Supplementary file Size Download File type/resource
GSE206486_gene_sample_count.xlsx 4.0 Mb (ftp)(http) XLSX
GSE206486_microRNA_sample_counts_with_family.xlsx 66.3 Kb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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