|
| Status |
Public on Feb 02, 2011 |
| Title |
Affymetrix Mouse liver gene expression profiling of Cross B6/J x A/J |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Summary Mapping the genetic architecture of RNA transcript abundances has potential for revealing molecular mechanisms underlying complex traits like disease. Gene expression microarrays allow monitoring genetic control on a whole transcriptome level, but validity and reproducibility of microarray data is a subject of ongoing scientific debate. Here we demonstrate how combining genetic and gene expression data provide a basis for biologically relevant assessment of the current state of microarray technology. We profile liver samples from a murine F2 intercross population using Affymetrix microarrays.
|
| |
|
| Overall design |
Tissue profiling in a mouse F2 cross. We analyzed 294 Liver samples.
|
| |
|
| Contributor(s) |
Chudin E, Kasarskis A, Castle J, Kulkarni A, Lejnine S, Schadt E |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Mar 16, 2010 |
| Last update date |
Mar 22, 2012 |
| Contact name |
Sergey Lezhnin |
| E-mail(s) |
sergey_lezhnin@merck.com
|
| Organization name |
Merck Research Laboratories
|
| Department |
Molecular Profiling
|
| Lab |
Data Analysis
|
| Street address |
33 AVENUE LOUIS PASTEUR
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL7368 |
Rosetta/Merck Mouse 430 2.0 RSTA Custom CDF microarray |
|
| Samples (294)
|
|
| This SubSeries is part of SuperSeries: |
| GSE20903 |
Mouse liver gene expression profiling of Cross B6/J x A/J |
|
| Relations |
| BioProject |
PRJNA129653 |
Less...
More...