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| Status |
Public on Jul 26, 2022 |
| Title |
Exosomal-microRNA transcriptome profiling of mice endothelial cells in response to high phosphorus treatment |
| Platform organisms |
Homo sapiens; Mus musculus; Rattus norvegicus |
| Sample organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
Using the highly sensitive miRNA array, we screened 3100 microRNAs abundant in the high phosphorus-treated endothelial cells derived exosome and we explored the functions of these miRNAs.
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| Overall design |
In this study, exosome samples from normal and high concentrations of inorganic phosphate-induced ECs were extracted to acquire the miRNA expression profiling. And the function of the abudant miRNAs were analyzed,which may provide potential therapeutic targets for arterial calcification in ESRD patients.
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| Contributor(s) |
Lin X, Shan S |
| Citation missing |
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| |
| Submission date |
Jul 25, 2022 |
| Last update date |
Jul 29, 2022 |
| Contact name |
Su-Kang Shan |
| E-mail(s) |
sukangshan@csu.edu.cn
|
| Phone |
18274980122
|
| Organization name |
Central South University
|
| Street address |
139 Middle Renmin Road
|
| City |
Changsha |
| ZIP/Postal code |
86 |
| Country |
China |
| |
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| Platforms (1) |
| GPL18058 |
Exiqon miRCURY LNA microRNA array, 7th generation [miRBase v18, condensed Probe_ID version] |
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| Samples (6)
|
| GSM6383082 |
A1: Normal phosphorus treated endothelial cells-exosome-Rep1 |
| GSM6383083 |
A2: Normal phosphorus treated endothelial cells-exosome-Rep2 |
| GSM6383084 |
A3: Normal phosphorus treated endothelial cells- exosome-Rep3 |
| GSM6383085 |
B1: High phosphorus treated endothelial cells-exosome-Rep1 |
| GSM6383086 |
B2: High phosphorus treated endothelial cells-exosome-Rep 2 |
| GSM6383087 |
B3: High phosphorus treated endothelial cells- exosome-Rep-3 |
|
| Relations |
| BioProject |
PRJNA862066 |
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