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Series GSE210176 Query DataSets for GSE210176
Status Public on Sep 08, 2022
Title Effect of depletion of OGT on gene expression during M2 polarization of macrophages
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary To investigate the function OGT in the regulation of M2 polarization of macrophages, we established IL-4-activated bone marrow-derived macrophages (BMDMs) from mice of wild-type control or Lyz2-Cre/Loxp-mediated knockout of OGT.
We then performed gene expression profiling analysis using data obtained from RNA-seq of wild-type (WT) and OGT-knockout (OGT-KO) macrophages at two time points during IL-4 (20ng/μl) sitmulation.
 
Overall design Comparative gene expression profiling analysis of RNA-seq data for WT and OGT-KO BMDMs.
 
Contributor(s) Cao X, Shi Q
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Aug 01, 2022
Last update date Sep 08, 2022
Contact name Qian Zhang
E-mail(s) oilpangpang@hotmail.com
Phone +8615921196443
Organization name Second military medical university
Street address xiangyin road 800
City shang hai
ZIP/Postal code 200433
Country China
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (4)
GSM6423008 Wild-type macrophages, 0h
GSM6423009 Wild-type macrophages, 24h
GSM6423010 OGT-KO macrophages, 0h
Relations
BioProject PRJNA864616

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE210176_Processed_data.txt.gz 588.5 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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