|
Status |
Public on Sep 08, 2022 |
Title |
Effect of depletion of OGT on gene expression during M2 polarization of macrophages |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
To investigate the function OGT in the regulation of M2 polarization of macrophages, we established IL-4-activated bone marrow-derived macrophages (BMDMs) from mice of wild-type control or Lyz2-Cre/Loxp-mediated knockout of OGT. We then performed gene expression profiling analysis using data obtained from RNA-seq of wild-type (WT) and OGT-knockout (OGT-KO) macrophages at two time points during IL-4 (20ng/μl) sitmulation.
|
|
|
Overall design |
Comparative gene expression profiling analysis of RNA-seq data for WT and OGT-KO BMDMs.
|
|
|
Contributor(s) |
Cao X, Shi Q |
Citation missing |
Has this study been published? Please login to update or notify GEO. |
|
Submission date |
Aug 01, 2022 |
Last update date |
Sep 08, 2022 |
Contact name |
Qian Zhang |
E-mail(s) |
oilpangpang@hotmail.com
|
Phone |
+8615921196443
|
Organization name |
Second military medical university
|
Street address |
xiangyin road 800
|
City |
shang hai |
ZIP/Postal code |
200433 |
Country |
China |
|
|
Platforms (1) |
GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
Samples (4)
|
|
Relations |
BioProject |
PRJNA864616 |