|
| Status |
Public on Sep 15, 2023 |
| Title |
MAF Amplification licenses Estrogen Receptor α to Drive Breast Cancer Metastasis [MAF ChIP-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by SNP array
|
| Summary |
We performed genome-wide mapping of MAF binding sites in control and MAF-overexpressing MCF7 cells to assess the consequences of estrogen (E2) stimulation on MAF recruitment to chromatin. To this end, we cultured MCF7 cells in hormone-deprived (HD) medium for 72 h and then E2 or vehicle was added for 1h prior to chromatin immunoprecipitation (ChIP). Samples were generated in triplicate. We report that MAF binding is largely independent of E2
|
| |
|
| Overall design |
Examination of MAF binding sites in control and MAF-overexpressing MCF7 cells before and after E2 stimulation.
|
| |
|
| Contributor(s) |
Llorente A, Ballaré C, Blanco E, Caballé A, Gomis R, Di Croce L |
| Citation(s) |
37945904 |
| Submission date |
Aug 05, 2022 |
| Last update date |
Dec 22, 2023 |
| Contact name |
Adria Caballe |
| E-mail(s) |
adria.caballe@irbbarcelona.org
|
| Organization name |
IRB
|
| Department |
biostatistics
|
| Street address |
C/ Baldiri Reixac 10
|
| City |
Barcelona |
| ZIP/Postal code |
08028 |
| Country |
Spain |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (6)
|
|
| This SubSeries is part of SuperSeries: |
| GSE210608 |
MAF Amplification licenses Estrogen Receptor α to Drive Breast Cancer Metastasis |
|
| Relations |
| BioProject |
PRJNA866478 |
Less...
More...