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| Status |
Public on May 05, 2023 |
| Title |
Epigenome analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation [methylation array] |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
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| Summary |
Genome wide DNA methylation profiling of a paraganglioma sample carrying the DLST-p.Y422C mutation. The Illumina Infinium EPIC Human DNA methylation Beadchip v1.2 was used to obtain a DNA methylation profile across approximately 850,000 CpGs. The main goal of this project was to find specific methylation profiles associated to the presence of mutations in the DLST gene of pheochromocytomas/paragangliomas.
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| Overall design |
Bisulphite converted DNA from the tumor sample was hybridised to the Illumina Infinium EPIC Human Methylation Beadchip
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| Contributor(s) |
Sara M, Mercedes R, Alberto C |
| Citation(s) |
37139660 |
| |
| Submission date |
Aug 09, 2022 |
| Last update date |
May 07, 2023 |
| Contact name |
Alberto Cascón |
| E-mail(s) |
acascon@cnio.es
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| Phone |
+34-91-224 69 47
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| Organization name |
Spanish National Cancer Research Centre (CNIO)
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| Department |
Human Cancer Genetics Program
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| Lab |
Hereditary Endocrine Cancer Group
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| Street address |
Melchor Fernández Almagro 3
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| City |
Madrid |
| ZIP/Postal code |
28029 |
| Country |
Spain |
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| Platforms (1) |
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| Samples (1) |
| GSM6438492 |
SAMPLE 1_genomic DNA from a paraganglioma sample carrying the DLST-p.Y422C mutation |
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| This SubSeries is part of SuperSeries: |
| GSE210810 |
Analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation |
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| Relations |
| BioProject |
PRJNA867592 |
