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Status |
Public on Dec 01, 2023 |
Title |
Rapid PTEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy [ChIP-Seq] |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
This study examines the reorganization of transcriptionally active chromatin that underlies the adaptive response of glioblastoma cells to radiotherapy.
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Overall design |
H3K27ac ChIPs were conducted in the DIPG4 cell line in the presence or absence of AZD or DMSO as control and subjected or not to radiation.
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Contributor(s) |
Sobral LM, Walker F, Danis E, Dahl N |
Citation missing |
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Submission date |
Aug 12, 2022 |
Last update date |
Dec 01, 2023 |
Contact name |
Nathan A Dahl |
E-mail(s) |
nathan.dahl@childrenscolorado.org
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Organization name |
University of Colorado School of Medicine
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Department |
Pediatrics
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Street address |
12800 E. 19th Ave., MS 8302
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City |
Aurora |
State/province |
CO |
ZIP/Postal code |
80045 |
Country |
USA |
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Platforms (1) |
GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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Samples (11)
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GSM6454192 |
H3K27Ac_histone H3_acetyl K27_DIPG4_with_DMSO 1 |
GSM6454193 |
H3K27Ac_histone H3_acetyl K27_DIPG4_with_DMSO 2 |
GSM6454194 |
Input_DIPG4_with_DMSO |
GSM6454195 |
H3K27Ac_histone H3_acetyl K27_DIPG4_with_DMSO_Radiation 1 |
GSM6454196 |
H3K27Ac_histone H3_acetyl K27_DIPG4_with_DSMO_Radiation 2 |
GSM6454197 |
Input_DIPG4_with_DMSO_Radiation_1 |
GSM6454198 |
Input_DIPG4_with_DMSO_Radiation_2 |
GSM6454199 |
H3K27Ac_histone H3_acetyl K27_DIPG4_with_AZD_Radiation 1 |
GSM6454200 |
H3K27Ac_histone H3_acetyl K27_DIPG4_with_AZD_Radiation 2 |
GSM6454201 |
Input_DIPG4_with_AZD_Radiation_1 |
GSM6454202 |
Input_DIPG4_with_AZD_Radiation_2 |
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This SubSeries is part of SuperSeries: |
GSE211149 |
Rapid PTEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy |
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Relations |
BioProject |
PRJNA869095 |