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Series GSE213777 Query DataSets for GSE213777
Status Public on Sep 23, 2022
Title MiRNAs array after SH3BP2 silencing in Gastrointestinal stromal tumor cells
Platform organisms Homo sapiens; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human betaherpesvirus 6B; Human gammaherpesvirus 8; Merkel cell polyomavirus; Betapolyomavirus hominis; Betapolyomavirus macacae
Sample organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary Silencing of the adaptor SH3BP2 impairs Gastrointestinal stromal tumors growth through miRNAs
We dissected SH3BP2 pathway in Gastrointestinal Stromal Tumor cells (GIST) performing a miRNA array in SH3BP2-silenced GIST cells
Overall design GIST cells lines :GIST 48 and GIST 882 were transduced with NTshRNA and SH3BP2 shRNA (seq21) lentivirus as described ( Serrano-Candelas, E. et al Mol. Oncol. 2018). MicroRNA array experiments were performed in triplicates and conducted by Exiqon, Services, Demark.
Contributor(s) Serrano Candelas E, Martin M
Citation(s) 36551682
Submission date Sep 20, 2022
Last update date Dec 23, 2022
Contact name Margarita Martin
Phone 934024541
Organization name University of Barcelona
Department Biomedicine
Street address Casanova 143
City Barcelona
State/province Barcelona
ZIP/Postal code 08036
Country Spain
Platforms (1)
GPL21599 miRCURY LNA microRNA Array, 7th generation, miRBase 20 (Gene ID version)
Samples (12)
GSM6594160 GIST_48, 21#3 shRNA-3BP2
GSM6594161 GIST_882, 21#3shRNA-3BP2
GSM6594162 GIST_882, 21#2shRNA-3BP2
BioProject PRJNA882427

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE213777_ExpAnalysis1.xlsx 97.4 Kb (ftp)(http) XLSX
GSE213777_ExpAnalysis2.xlsx 97.6 Kb (ftp)(http) XLSX
GSE213777_ExpAnalysis3.xlsx 97.2 Kb (ftp)(http) XLSX
GSE213777_RAW.tar 32.7 Mb (http)(custom) TAR (of TXT)
GSE213777_ThresholdFilteredData.xlsx 175.0 Kb (ftp)(http) XLSX
GSE213777_norm.xlsx 1.0 Mb (ftp)(http) XLSX
Processed data included within Sample table
Processed data are available on Series record

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