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| Status |
Public on Jun 07, 2023 |
| Title |
IBD single cell data from colonic mucosa |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Inflammatory bowel diseases (IBDs) including ulcerative colitis (UC) and Crohn’s disease (CD) are chronic inflammatory diseases with increasing worldwide prevalence that show a perplexing heterogeneity in manifestations and response to treatment. We applied single cell RNA sequencing (scRNAseq) a to colonic tissue from a combined healthy, UC and CD cohort.
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| Overall design |
Colonic cells from Healthy controls (6), Ulcerative Colitis (6) and Crohn's disease (6) patients were isolated and analyzed using scRNAseq.
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| Contributor(s) |
Garrido-Trigo A, Salas A |
| Citation(s) |
37495570 |
| Submission date |
Oct 03, 2022 |
| Last update date |
Sep 29, 2023 |
| Contact name |
Azucena Salas |
| E-mail(s) |
asalas1@recerca.clinic.cat
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| Organization name |
IDIBAPS
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| Department |
Gastroenterology
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| Street address |
Rosselló, 149-153
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| City |
Barcelona |
| ZIP/Postal code |
08036 |
| Country |
Spain |
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| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (18)
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| GSM6614351 |
HC 4, scRNAseq, sigma |
| GSM6614352 |
HC 5, scRNAseq, sigma |
| GSM6614353 |
HC 6, scRNAseq, sigma |
| GSM6614354 |
UC 1, scRNAseq, sigma |
| GSM6614355 |
UC 2, scRNAseq, transverse colon |
| GSM6614356 |
UC 3, scRNAseq, rectum |
| GSM6614357 |
UC 4, scRNAseq, sigma |
| GSM6614358 |
UC 5, scRNAseq, rectum |
| GSM6614359 |
UC 6, scRNAseq, rectum |
| GSM6614360 |
CD 1, scRNAseq, ascending colon |
| GSM6614361 |
CD 2, scRNAseq, sigma |
| GSM6614362 |
CD 3, scRNAseq, descending colon |
| GSM6614363 |
CD 4, scRNAseq, sigma |
| GSM6614364 |
CD 5, scRNAseq, sigma |
| GSM6614365 |
CD 6, scRNAseq, sigma |
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| Relations |
| BioProject |
PRJNA886695 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE214695_RAW.tar |
846.0 Mb |
(http)(custom) |
TAR (of MTX, TSV) |
| GSE214695_cell_annotation.csv.gz |
478.9 Kb |
(ftp)(http) |
CSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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